Vorasidenib | AG-881 | 1644545-52-7

规格	库存	目录价	会员专享价	数量
2 mg	In-stock	￥526.00	登录后可见	- +
5 mg	In-stock	￥966.00	登录后可见	- +
10 mg	In-stock	￥1638.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

2 mg

In-stock

￥526.00

登录后可见

- +

5 mg

In-stock

￥966.00

登录后可见

- +

10 mg

In-stock

￥1638.00

登录后可见

- +

基本信息

英文名称	Vorasidenib \| AG-881
中文名称	6-(6-氯-2-吡啶基)-N2,N4-双[(1R)-2,2,2-三氟-1-甲基乙基]-1,3,5-三嗪-2,4-二胺
CAS号	1644545-52-7
分子式	C14H13ClF6N6
分子量	414.74
外观	White to off-white

产品详情

Vorasidenib (AG-881) is an orally available, brain penetrant second-generation dual mutant isocitrate dehydrogenases 1 and 2 (mIDH1/2) inhibitor. Vorasidenib (AG-881) exhibits nanomolar inhibition of (D)-2-hydroxyglutarate (D-2-HG), and the IC₅₀ ranges of 0.04~22 nM against IDH1 R132C, IDH1 R132G, IDH1 R132H and IDH1 R132S and 7~14 nM against IDH2 R140Q and 130 nM against IDH2 R172K.

6-(6-氯-2-吡啶基)-N2,N4-双[(1R)-2,2,2-三氟-1-甲基乙基]-1,3,5-三嗪-2,4-二胺

Vorasidenib | AG-881

化学品安全说明书(MSDS)

质检证书(COA)