23604-59-5 | TMC 435350 | Simeprevir | TMC435

规格	库存	目录价	会员专享价	数量
2 mg	3-5days	￥436.00	登录后可见	- +
5 mg	3-5days	￥688.00	登录后可见	- +
10 mg	3-5days	￥1066.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

2 mg

3-5days

￥436.00

登录后可见

- +

5 mg

3-5days

￥688.00

登录后可见

- +

10 mg

3-5days

￥1066.00

登录后可见

- +

基本信息

英文名称	Simeprevir (Synonyms: TMC435; TMC435350)
中文名称	西咪匹韦 \| 司美匹韦 \| 西米普韦
CAS号	923604-59-5
分子式	C38H47N5O7S2
分子量	749.94
外观	White to off-white powder
储存条件	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

产品详情

Simeprevir (TMC435; TMC435350) is an oral, potent and highly specific hepatitis C virus (HCV) NS3/4A protease inhibitor with a K_i of 0.36 nM. Simeprevir inhibits HCV replication with an EC₅₀ of 7.8 nM. Simeprevir also potently suppresses SARS-CoV-2 replication and synergizes with Remdesivir. Simeprevir inhibits the main protease (M^pro) and the RNA-dependent RNA polymerase (RdRp) of SARS-CoV-2, and also modulates host immune responses.
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