| 英文名称 | (±)-2-Oxo clopidogrel (Synonyms: (±)-SR-121683) |
|---|---|
| 中文名称 | (±)-SR-121683 |
| CAS号 | 109904-27-0 |
| 分子式 | C16H16ClNO3S |
| 分子量 | 337.82 |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| 英文名称 | (±)-2-Oxo clopidogrel (Synonyms: (±)-SR-121683) |
|---|---|
| 中文名称 | (±)-SR-121683 |
| CAS号 | 109904-27-0 |
| 分子式 | C16H16ClNO3S |
| 分子量 | 337.82 |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
2-oxo Clopidogrel is an intermediary metabolite of Clopidogrel. Clopidogrel is a prodrug that is converted to its active metabolite via two sequential oxidative steps. The first step leads to formation of 2-oxo clopidogrel, followed by conversion to the active metabolite, which binds specifically and irreversibly to the platelet P2Y12 purinergic receptor, inhibiting ADP-mediated platelet activation and aggregation.