PLX5622; CAS: 1303420-67-8

规格	库存	目录价	会员专享价	数量
1 mg	3-5 days	￥366.00	登录后可见	- +
5 mg	3-5 days	￥966.00	登录后可见	- +
10 mg	3-5 days	￥1366.00	登录后可见	- +
25 mg	3-5 days	￥2286.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

1 mg

3-5 days

￥366.00

登录后可见

- +

5 mg

3-5 days

￥966.00

登录后可见

- +

10 mg

3-5 days

￥1366.00

登录后可见

- +

25 mg

3-5 days

￥2286.00

登录后可见

- +

基本信息

英文名称	PLX5622
中文名称	6-氟-N-((5-氟-2-甲氧基吡啶-3-基)甲基)-5-((5-甲基-1H-吡咯并[2,3-b]吡啶-3-基)甲基)吡啶 -2-胺;PLX5622
CAS号	1303420-67-8
分子式	C21H19F2N5O
分子量	395.41
MDL	MFCD32201039

产品详情

PLX5622, a highly selective CSF-1R inhibitor with an IC50 of < 10 nmol/L and over 20-fold selectivity over KIT and FLT3, is a brain-penetrant, orally active compound with an IC50 of 0.016 μM and a Ki of 5.9 nM. It enables targeted microglial cell elimination during pathology development and exhibits favorable pharmacokinetics across multiple animal species.

6-氟-N-((5-氟-2-甲氧基吡啶-3-基)甲基)-5-((5-甲基-1H-吡咯并[2,3-b]吡啶-3-基)甲基)吡啶 -2-胺;PLX5622

PLX5622

化学品安全说明书(MSDS)