buy Lapaquistat acetate| Lapaquistat acetatesupplier | purchase Lapaquistat acetate ；(Synonyms: TAK-475); CAS: 189060-13-7; squalene synthase inhibitor

规格	库存	目录价	会员专享价	数量
1 mg	3-5 days	￥1488.00	登录后可见	- +
2 mg	3-5 days	￥2266.00	登录后可见	- +
5 mg	3-5 days	￥3626.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

1 mg

3-5 days

￥1488.00

登录后可见

- +

2 mg

3-5 days

￥2266.00

登录后可见

- +

5 mg

3-5 days

￥3626.00

登录后可见

- +

基本信息

英文名称	Lapaquistat acetate (Synonyms: TAK-475)
中文名称	2-(1-(2-((3R,5S)-1-(3-乙酰氧基-2,2-二甲基丙基)-7-氯-5-(2,3-二甲氧基苯基)-2-氧代-1,2,3,5-四氢苯并[e][1,4]氧氮杂卓-3-基)乙酰基)哌啶-4-基)乙酸
CAS号	189060-13-7
分子式	C33H41ClN2O9
分子量	645.14
MDL	MFCD06407873
外观	White to off-white powder
储存条件	Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.

产品详情

Lapaquistat acetate, a potent squalene synthase inhibitor, impedes the conversion of farnesyl diphosphate (FPP) to squalene, a key step in cholesterol synthesis. Utilized in treating Mevalonate Kinase Deficiency (MKD), an autosomal recessive disorder, it significantly reduces low-density lipoprotein cholesterol levels. However, its use may be accompanied by liver damage, a known side effect that warrants monitoring.

2-(1-(2-((3R,5S)-1-(3-乙酰氧基-2,2-二甲基丙基)-7-氯-5-(2,3-二甲氧基苯基)-2-氧代-1,2,3,5-四氢苯并[e][1,4]氧氮杂卓-3-基)乙酰基)哌啶-4-基)乙酸

Lapaquistat acetate (Synonyms: TAK-475)

化学品安全说明书(MSDS)