RI-1 | 415713-60-9

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库存

目录价

会员专享价

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基本信息

英文名称	RI-1 (Synonyms:RI1; RAD51 inhibitor 1)
中文名称	3-氯-1-(3,4-二氯苯基)-4-(4-吗啉基)-1H-吡咯-2,5-二酮
CAS号	415713-60-9
分子式	C14H11Cl3N2O3
分子量	361.61
MDL	MFCD00814248

产品详情

RI-1 is a cell-permeable RAD51 inhibitor that binds covalently to the protein surface at Cysteine 319. RI-1 disrupts homologous recombination in human cells. RI-1 is a cell-permeable RAD51 inhibitor. RI-1 is a RAD51 inhibitor, with IC50s ranging from 5 to 30 μM. RI-1 binds covalently to the surface of RAD51 protein at cysteine 319. RI-1 inactivates RAD51 by directly binding to a protein surface that serves as an interface between protein subunits in RAD51 filaments. RI-1 can disrupt homologous recombination in human cells.
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3-氯-1-(3,4-二氯苯基)-4-(4-吗啉基)-1H-吡咯-2,5-二酮

RI-1 (Synonyms:RI1; RAD51 inhibitor 1)

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