| 英文名称 | A-803467 |
|---|---|
| 中文名称 | 5-(4-氯苯基)-N-(3,5-二甲氧基苯基)呋喃-2-甲酰胺 |
| CAS号 | 944261-79-4 |
| 分子式 | C19H16NO4Cl |
| 分子量 | 357.79 |
| MDL | MFCD10574689 |
| 英文名称 | A-803467 |
|---|---|
| 中文名称 | 5-(4-氯苯基)-N-(3,5-二甲氧基苯基)呋喃-2-甲酰胺 |
| CAS号 | 944261-79-4 |
| 分子式 | C19H16NO4Cl |
| 分子量 | 357.79 |
| MDL | MFCD10574689 |
A-803467 is a potent and selective tetrodotoxin-resistant Nav1.8 sodium channel blocker (IC50=8 nM). A-803467 has shown significant anti-nociception in neuropathic and inflammatory pain models. A-803467 enhances the chemosensitivity of conventional anticancer agents through interaction with the ATP-binding cassette subfamily G member 2 (ABCG2) transporter.