Soquelitinib | 2226636-04-8 | CPI-818 | CPI818

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库存

目录价

会员专享价

数量

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基本信息

英文名称	Soquelitinib (Synonyms: CPI-818)
中文名称	(R)-N-(5-((5-(4-丙烯酰基-3-甲基-1,4-二氮杂环庚烷-1-羰基)-4-甲氧基-2-甲基苯基)硫基)噻唑-2-基)环丙烷甲酰胺;索喹替尼
CAS号	2226636-04-8
分子式	C25H30N4O4S2
分子量	514.66

产品详情

Soquelitinib (CPI-818) is an orally active and highly selective covalent interleukin-2-inducible kinase (ITK) inhibitor. Soquelitinib is active in six different models of T cell-mediated inflammatory and immune disease, including acute and chronic asthma, pulmonary fibrosis, systemic sclerosis (scleroderma), psoriasis, and acute graft versus host disease with Th2 cytokine product inhibition. Soquelitinib increases tumor infiltration of normal CD8+ cells that possess enhanced T effector function.
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(R)-N-(5-((5-(4-丙烯酰基-3-甲基-1,4-二氮杂环庚烷-1-羰基)-4-甲氧基-2-甲基苯基)硫基)噻唑-2-基)环丙烷甲酰胺;索喹替尼

Soquelitinib (Synonyms: CPI-818)

化学品安全说明书(MSDS)