英文名称 | Nivolumab (anti-PD-1) (Synonyms:BMS-936558; ONO-4538; MDX-1106) |
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中文名称 | 纳武单抗 (anti-PD-1); 尼鲁单抗 |
CAS号 | 946414-94-4 |
分子量 | 143599.09 |
外观 | Colorless to light yellow liquid |
储存条件 | Sealed and stored at ≤-80℃, away from light. Avoid freeze-thaw cycles |
英文名称 | Nivolumab (anti-PD-1) (Synonyms:BMS-936558; ONO-4538; MDX-1106) |
---|---|
中文名称 | 纳武单抗 (anti-PD-1); 尼鲁单抗 |
CAS号 | 946414-94-4 |
分子量 | 143599.09 |
外观 | Colorless to light yellow liquid |
储存条件 | Sealed and stored at ≤-80℃, away from light. Avoid freeze-thaw cycles |
1.Nivolumab (anti-PD-1) is a genetically engineered, fully human immunoglobulin (Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1 (PD-1,PCD-1) with immune checkpoint inhibitory and antineoplastic activities. MW : 143.597 KD.
2.Nivolumab is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody to treat advanced (metastatic) non-small cell lung cancer.