Anti-Human PCSK9 Monoclonal Antibody(Evolocumab) | AMG 145

规格	库存	目录价	会员专享价	数量
1 mg	3-5days	￥3000.00	登录后可见	- +
5 mg	3-5days	￥12500.00	登录后可见	- +
10 mg	3-5days	￥20000.00	登录后可见	- +
50 mg	3-5days	￥80000.00	登录后可见	- +
100 mg	3-5days	￥125000.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

1 mg

3-5days

￥3000.00

登录后可见

- +

5 mg

3-5days

￥12500.00

登录后可见

- +

10 mg

3-5days

￥20000.00

登录后可见

- +

50 mg

3-5days

￥80000.00

登录后可见

- +

100 mg

3-5days

￥125000.00

登录后可见

- +

基本信息

英文名称	Anti-Human PCSK9 Monoclonal Antibody(Evolocumab); AMG 145
中文名称	依洛尤单抗; 依伏库单抗
CAS号	1256937-27-5
外观	Colorless to light yellow (Solution)
储存条件	Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.

产品详情

Evolocumab (AMG 145) is a human monoclonal antibody that inhibits PCSK9. Evolocumab is used in the study of hypercholesterolemia and atherosclerotic cardiovascular disease. Evolocumab binds to circulating PCSK9 protein and inhibits its binding to LDLR. Evolocumab has antioxidant and cytoprotective activities against H2O2-induced oxidative damage to endothelial cells. Evolocumab may also negatively regulate activation of the TLR-4/NF-κB signaling pathway to prevent inflammation.

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