| 英文名称 | Anti-CD138 (indatuximab ravtansine biosimilar) mAb |
|---|---|
| 中文名称 | 雷英妥昔单抗 |
| CAS号 | 1238517-16-2 |
| 储存条件 | 2 weeks, 2-8℃ under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
| 英文名称 | Anti-CD138 (indatuximab ravtansine biosimilar) mAb |
|---|---|
| 中文名称 | 雷英妥昔单抗 |
| CAS号 | 1238517-16-2 |
| 储存条件 | 2 weeks, 2-8℃ under sterile conditions after reconstitution. Avoid repeated freeze-thaw. -80°C for a long-term storage. |
Indatuximab ravtansine (BT062) is an antibody-drug conjugate (ADC) based on a murine/human chimeric form of B-B4 (CD138-specific antibody), which is covalently conjugated to the maytansinoid drug DM4 via a disulfide bond-based linker. Maytansinoids are structural analogs of the cytotoxic agent maytansine, which has been evaluated in phase I and phase II clinical trials.