| 英文名称 | Oportuzumab Monatox |
|---|---|
| 中文名称 | 莫妥组单抗 |
| CAS号 | 945228-48-8 |
| 储存条件 | Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light. |
| 英文名称 | Oportuzumab Monatox |
|---|---|
| 中文名称 | 莫妥组单抗 |
| CAS号 | 945228-48-8 |
| 储存条件 | Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light. |
Oportuzumab monatox, also known as VB4-845, is a recombinant fusion protein comprising a humanized anti-EpCAM single-chain antibody linked to Pseudomonas exotoxin A (ETA (252-608)). Once bound to the cancer cell, OM is internalized and the toxin moiety released into the cytosol where it induces apoptosis.