| 英文名称 | Cixutumumab |
|---|---|
| 中文名称 | 西妥木单抗 |
| CAS号 | 947687-12-9 |
| 英文名称 | Cixutumumab |
|---|---|
| 中文名称 | 西妥木单抗 |
| CAS号 | 947687-12-9 |
Cixutumumab (IMC-A12) is a humanized anti-IGF-1R monoclonal antibody with high affinity that inhibits ligand-dependent receptor activation and downstream signaling. Cixutumumab also mediates the internalization and degradation of IGF-IR. Cixutumumab shows broad-spectrum anti-tumour activity and can be used in studies of cancers such as lung cancer, malignancies, leukaemia, non-small cell lung cancer and prostate cancer.