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地努妥昔单抗

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Anti-Human Ganglioside GD2 (Synonyms: Dinutuximab; APN-311)

产品编号:CLA1331 CAS No.:1363687-32-4 MDLNo: 分子式: 分子量:
规格 库存 目录价 会员专享价 数量
1 mg 3-5days ¥3000.00 登录后可见
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5 mg 3-5days ¥12500.00 登录后可见
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10 mg 3-5days ¥20000.00 登录后可见
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50 mg 3-5days ¥80000.00 登录后可见
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100 mg 3-5days ¥125000.00 登录后可见
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基本信息
英文名称 Anti-Human Ganglioside GD2 (Synonyms: Dinutuximab; APN-311)
中文名称地努妥昔单抗
CAS号1363687-32-4
储存条件 Store at 2 to 8 °C for 1-2 weeks. Store at -20 °C for 12 months. Store at -80 °C for long term storage. Use a manual defrost freezer and avoid repeated freeze-thaw cycles, away from light.
产品详情

1. Dinutuximab (Anti-GD2) is a chimeric mouse/human monoclonal antibody that targets ganglioside GD2 and induces antibody-dependent cell-mediated cytotoxicity and complement-dependent cytotoxicity against GD2-expressing tumor cells. It has potential antineoplastic activity. MW: 145.5 KD.

2. Dinutuximab (Unituxin; APN-311) is a chimeric, human-murine, anti-GD2 monoclonal antibody. Dinutuximab potently enlongs event-free survival and overall survival, in high-risk neuroblastoma treatment, in combination with granulocyte-macrophage colony-stimulating factor (GM-CSF), aldesleukin (interleukin-2 [IL-2]), and isotretinoin (13-cis-retinoic acid [RA]).

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