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基本信息

英文名称	Anti-Human IGF1RxHer3 Bispecific Antibody (Istiratumab; MM 141; MM-005)
中文名称	艾司妥单抗
CAS号	1509928-04-4

产品详情

Istiratumab, a bispecific mAb against IGF-1R and ErbB3, promotes receptor degradation via proteasomes, inhibiting AKT in pancreatic cancer cells and blocking PI3K/MAPK in ovarian cancer. It enhances chemo efficacy, potentiating paclitaxel, cisplatin, and doxorubicin in preclinical studies.

艾司妥单抗

Anti-Human IGF1RxHer3 Bispecific Antibody (Istiratumab; MM 141; MM-005)

化学品安全说明书(MSDS)