英文名称 | Anti-Human F9xF10 Bispecific Antibody(Emicizumab;RO 5534262, ACE 910;RG6013,hBS910;coagulation factor 10, coagulation factor X;coagulation factor 9, coagulation factor IX) |
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中文名称 | 依米赛珠单抗; 艾美赛珠单抗 |
CAS号 | 1610943-06-0 |
储存条件 | store at -20°C |
英文名称 | Anti-Human F9xF10 Bispecific Antibody(Emicizumab;RO 5534262, ACE 910;RG6013,hBS910;coagulation factor 10, coagulation factor X;coagulation factor 9, coagulation factor IX) |
---|---|
中文名称 | 依米赛珠单抗; 艾美赛珠单抗 |
CAS号 | 1610943-06-0 |
储存条件 | store at -20°C |
Emicizumab is a bispecific monoclonal antibody that simulates the function of coagulation Factor VIII by bridging activated Factor IX and Factor X. It's approved for routine prophylaxis to prevent or reduce bleeding episodes in adults and children with hemophilia A, with or without Factor VIII inhibitors.
A hemophilia A mouse model for the in vivo assessment of emicizumab function.
PMID: 32369559 DOI: 10.1182/blood.2019004334