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卡度尼利单抗

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Anti-Human PD-1xCTLA-4 Bispecific Antibody(Cadonilimab)

产品编号:CLA1494 CAS No.:2394841-59-7 MDLNo: 分子式: 分子量:
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基本信息
英文名称 Anti-Human PD-1xCTLA-4 Bispecific Antibody(Cadonilimab)
中文名称卡度尼利单抗
CAS号2394841-59-7
储存条件 -80°C for one-year storage. Avoid repeated freeze-thaw.
产品详情

Cadonilimab is a pioneering bispecific antibody targeting PD-1 and CTLA-4,it blocks both PD-1 and CTLA-4 pathways, thereby relieving their corresponding immunosuppressive effects and reversing tumor specific T cell exhaustion. Cadonilimab significantly downregulates Fc-mediated effector functions, including antibody-dependent cell-mediated cytotoxicity (ADCC), antibody-dependent cellular phagocytosis (ADCP), complement dependent cytotoxicity (CDC). Cadonilimab can be used for research of metastatic cervical cancer, as well as other malignancies such as gastric cancer, GEJ adenocarcinoma and non-small cell lung cancer (NSCLC).

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