| 英文名称 | Cholera Toxin Subunit B(CTB) | Cholera Toxin B Subunit (CTB) |
|---|---|
| 中文名称 | 霍乱毒素亚型B(CTB) |
| CAS号 | 131096-89-4 |
| 分子量 | 11kd |
| 外观 | White powder |
| 储存条件 | 2-8℃ |
| 英文名称 | Cholera Toxin Subunit B(CTB) | Cholera Toxin B Subunit (CTB) |
|---|---|
| 中文名称 | 霍乱毒素亚型B(CTB) |
| CAS号 | 131096-89-4 |
| 分子量 | 11kd |
| 外观 | White powder |
| 储存条件 | 2-8℃ |
Cholera toxin belongs to the AB5 –subunit family oftoxins.The native hexameric protein has a molecular mass of ~85 kDa and contains two subunits. It consists of a single A subunit (~27.2 kDa), responsible for the ADP-ribosylation activity, and five B subunits(~11.6 kDa each), which are arranged as a pentameric ring with an apparent 5-fold symmetry and are associated with the cell surface receptor binding and subsequent internalization (transmembrane transport)of the enzymatic component.
PMID: 9726431 DOI: 10.1002/(SICI)1097-4547(19980901)53:5<605::AID-JNR10>3.0.CO;2-#
Aggregation of lipid rafts accompanies signaling via the T cell antigen receptor.
doi: 10.1083/jcb.147.2.447