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高三尖杉酯碱

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Homoharringtonine (HHT) | Omacetaxine mepesuccinate

产品编号:HL1109 CAS No.:26833-87-4 MDLNo:MFCD05618221 分子式:C29H39NO9 分子量:545.62
规格 库存 目录价 会员专享价 数量
5 mg 3-5 days ¥406.00 登录后可见
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10 mg 3-5 days ¥668.00 登录后可见
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25 mg 3-5 days ¥1088.00 登录后可见
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50 mg 3-5 days ¥1766.00 登录后可见
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基本信息
英文名称 Homoharringtonine (HHT) | Omacetaxine mepesuccinate
中文名称高三尖杉酯碱
CAS号26833-87-4
分子式C29H39NO9
分子量545.62
MDLMFCD05618221
外观Off-white to yellow powder
储存条件 4°C, protect from light
产品详情

Homoharringtonine (Omacetaxine mepesuccinate; HHT) is a cytotoxic alkaloid derived from the Cephalotaxus tree, known for its significant antitumor properties. HHT acts primarily by inhibiting translation elongation, which disrupts protein synthesis crucial for cancer cell survival. This mechanism leads to the rapid degradation of several short-lived proteins, including Mcl-1 and c-Myc, triggering apoptosis in various cancer types, particularly in hematological malignancies such as acute myeloid leukemia (AML).

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