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依氟鸟氨酸盐酸盐一水合物

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Catalog No:CL1653 CAS No.:96020-91-6 MDLNo: Formula:C6H15ClF2N2O3 MW:236.64
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Product Overview
Product Name Eflornithine Hydrochloride Monohydrate
CAS96020-91-6
FormulaC6H15ClF2N2O3
MW236.64
AppearanceWhite to off-white powder
Storage conditionDry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Eflornithine, also known as Difluoromethylornithine, is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells.

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