Home > Category > Signaling Pathways > Cytoskeletal Signaling > Microtubule/Tubulin > Ixabepilone | BMS-247550 | Aza-epothilone B

伊沙匹隆

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Catalog No:CL1656 CAS No.:219989-84-1 MDLNo: Formula:C27H42N2O5S MW:506.70
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Product Overview
Product Name Ixabepilone | BMS-247550 | Aza-epothilone B
CAS219989-84-1
FormulaC27H42N2O5S
MW506.70
AppearanceWhite to off-white powder
Storage condition4°C, protect from light
Product details

Ixabepilone is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell cycle and inducing tumor cell apoptosis.


Related literature

Hunt Discovery of Ixabepilone.

https://doi.org/10.1158/1535-7163.MCT-08-0999

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