Home > Category > Signaling Pathways > DNA Damage/DNA Repair > DNA Alkylator/Crosslinker > Carboplatin (Synonyms: NSC 241240; 卡铂)

顺-二氨-1,1-环丁烷基二羧酸铂

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Catalog No:CL2199 CAS No.:41575-94-4 MDLNo:MFCD00070464 Formula:C6H12N2O4Pt MW:371.25
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Product Overview
Product Name Carboplatin (Synonyms: NSC 241240; 卡铂)
CAS41575-94-4
FormulaC6H12N2O4Pt
MW371.25
MDLMFCD00070464
AppearanceWhite to off-white powder
Storage condition Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
Product details

Carboplatin, a derivative of CDDP, is a DNA synthesis inhibitor which binds to DNA, inhibits replication and transcription and induces cell death and interfers with the cell's repair mechanism in A2780, SKOV-3, IGROV-1, and HX62 cells. It induces the formation of DNA interstrand crosslinks and DNA-protein crosslinks. Solutions are unstable and should be fresh-prepared.DMSO is not recommended to dissolve platinum-based drugs, which can easily lead to drug inactivation.

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