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Catalog No：CL2641A CAS No.：158876-82-5 MDLNo： Formula：C26H26ClN3 MW：415.96

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Product Overview

Product Name	Rupatadine (Synonyms: UR-12592)
CAS	158876-82-5
Formula	C26H26ClN3
MW	415.96
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Rupatadine (UR-12592) is a potent, orally active and long-lasting dual PAF/H1 antagonist, with Kis of 0.55 μM and 0.1 μM, respectively. Rupatadine can be used for the research of allergic rhinitis and urticaria.

Related literature

Rupatadine, a new potent, orally active dual antagonist of histamine and platelet-activating factor (PAF).

PMID: 8996188

Rupatadine protects against pulmonary fibrosis by attenuating PAF-mediated senescence in rodents.

PMID: 23869224 PMCID: PMC3711902 DOI: 10.1371/journal.pone.0068631

In vitro inhibitory effect of rupatadine on histamine and TNF-alpha release from dispersed canine skin mast cells and the human mast cell line HMC-1

PMID: 23869224 PMCID: PMC3711902 DOI: 10.1371/journal.pone.0068631