252916-29-3 | SU 6668(TSU-68)

Size	Availability	Price(USD)	VIP Price (USD)	Quantity
There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	Orantinib \| SU 6668 \| TSU-68
CAS	252916-29-3
Formula	C18H18N2O3
MW	310.35
Appearance	Yellow to orange powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation. It shows little effect against IGF-1R, Met, Src, Lck, Zap70, Abl and CDK2 and does not suppresses EGFR.

Related literature

Augmentation of chemotherapeutic infusion effect by TSU-68, an oral targeted antiangiogenic agent, in a rabbit VX2 liver tumor model

PMID: 21184227 DOI: 10.1007/s00270-010-0081-y

In vivo assessment of antiangiogenic activity of SU6668 in an experimental colon carcinoma model.

PMID: 14760097 DOI: 10.1158/1078-0432.ccr-0828-03