SL 327 | 305350-87-2

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Size

Availability

Price(USD)

VIP Price (USD)

Quantity

There is no price information at the moment, you can send an inquiry,and we will reply to you as soon as possible.

Product Overview

Product Name	SL 327
CAS	305350-87-2
Formula	C16H12F3N3S
MW	335.35
MDL	MFCD06411432
Appearance	White to off-white powder
Storage condition	Store in a dry and dark sealed container, short-term (weeks to months) storage at 0-4 ℃, long-term (months to years) storage at -20 ℃.

Product details

SL327 is a selective inhibitor for MEK1/2 with IC50 of 0.18 μM/ 0.22 μM, no activity towards Erk1, MKK3, MKK4, c-JUN, PKC, PKA, or CamKII; capable of transport through the blood-brain barrier.

Related literature

Regulation of cyclooxygenase-2 induction in the mouse uterus during decidualization. An event of early pregnancy.

PMID: 10969080 DOI: 10.1074/jbc.M006168200

Current Development Status of MEK Inhibitors.

PMID: 28954413 PMCID: PMC6151813 DOI: 10.3390/molecules22101551

A necessity for MAP kinase activation in mammalian spatial learning

PMID: 10541468 PMCID: PMC311312 DOI: 10.1101/lm.6.5.478

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History

CL2945

SL 327

305350-87-2 98+%

3-氨基-3-((4-氨基苯基)硫基)-2-(2-(三氟甲基)苯基)丙烯腈

Chemical safety data sheet(MSDS)