Home > Category > Signaling Pathways > Metabolism > Pyruvate Kinase > TEPP-46 (Synonyms: ML-265)

6-(3-氨基苄基)-4-甲基-2-(甲基亚磺酰基)-4H-噻吩并[2',3':4,5]吡咯并[2,3-d]哒嗪-5(6H)-酮

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Catalog No：CL3125 CAS No.：1221186-53-3 MDLNo：MFCD23160747 Formula：C17H16N4O2S2 MW：372.46

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Size	Availability	Price(USD)	VIP Price (USD)	Quantity
5 mg	3-5 days	￥698.00	Visible after login	- +
10 mg	3-5 days	￥1066.00	Visible after login	- +
25 mg	3-5 days	￥1566.00	Visible after login	- +
50 mg	3-5 days	￥2266.00	Visible after login	- +

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Product Overview

Product Name	TEPP-46 (Synonyms: ML-265)
CAS	1221186-53-3
Formula	C17H16N4O2S2
MW	372.46
MDL	MFCD23160747
Appearance	White to light yellow powder
Storage condition	Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.

Product details

TEPP-46, also known as ML265, is a potent and selective PKM2 activator with an AC50 of 92 nM, exhibiting high selectivity over PKM1, PKR, and PKL.

Related literature

PMID: 22922757 PMCID: PMC3711671 DOI: 10.1038/nchembio.1060

PMID: 25565206 PMCID: PMC5198835 DOI: 10.1016/j.cmet.2014.12.005

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