Alvimopan dihydrate (Synonyms: ADL 8-2698 dihydrate; LY 246736 dihydrate);CAS: 170098-38-1

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Product Overview

Product Name	Alvimopan dihydrate (Synonyms: ADL 8-2698 dihydrate; LY 246736 dihydrate)
CAS	170098-38-1
Formula	C25H36N2O6
MW	460.56
MDL	MFCD00927248
Appearance	White to off-white powder
Storage condition	Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.

Product details

Alvimopan dihydrate (ADL 8-2698 dihydrate) is a selective μ-opioid receptor antagonist with an IC50 of 1.7 nM, exhibiting high potency and oral activity. It demonstrates significant selectivity for the μ-opioid receptor (Ki=0.47 nM) over κ- and δ-opioid receptors (Kis=100, 12 nM, respectively), making it a valuable tool in postoperative ileus research.

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