I-OMe-Tyrphostin AG 538

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Product Overview

Product Name	I-OMe-Tyrphostin AG 538 (Synonyms: I-OMe-AG 538)
CAS	1094048-77-7
Formula	C17H12INO5
MW	437.19

Product details

I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells. I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC50 of 1 μM.
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History

CLP1138

cis-Fmoc-Pro(4-N3)-OH (Synonyms: Fmoc-(2S, 4S)-4-azidoproline; (2S,4S)-4-azido-1-(9H-fluoren-9-ylmethoxycarbonyl)pyrrolidine-2-carboxylic acid; (2S,4S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)-4-azidopyrrolidine-2-carboxylic acid)

263847-08-1 98+%

CL3723

I-OMe-Tyrphostin AG 538 (Synonyms: I-OMe-AG 538)

1094048-77-7 98+%

CL-NBP0141

Recombinant Human AD7c-NTP antigen

N/A ≥90 % as determined by SDS-PAGE

Chemical safety data sheet(MSDS)