Temozolomide | NSC 362856 | CCRG 81045 | TMZ

规格	库存	目录价	会员专享价	数量
500 mg	In-stock	￥688.00	登录后可见	- +
1 g	In-stock	￥1068.00	登录后可见	- +
5 g	In-stock	￥2688.00	登录后可见	- +

规格

库存

目录价

会员专享价

数量

500 mg

In-stock

￥688.00

登录后可见

- +

1 g

In-stock

￥1068.00

登录后可见

- +

5 g

In-stock

￥2688.00

登录后可见

- +

基本信息

英文名称	Temozolomide \| NSC 362856 \| CCRG 81045 \| TMZ
中文名称	3-甲基-4-氧代-3,4-二氢咪唑并[5,1-d][1,2,3,5]四嗪-8-甲酰胺；替莫唑胺
CAS号	85622-93-1
分子式	C6H6N6O2
分子量	194.15
MDL	MFCD00866492
外观	Off-white crystalline powder
储存条件	-20°C, protect from light, stored under nitroge

产品详情

1. TMZ(Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.

2.Temozolomide (NSC 362856) is an oral active DNA alkylating agent that crosses the blood-brain barrier. Temozolomide is also a proautophagic and proapoptotic agent. Temozolomide is effective against tumor cells that are characterized by low levels of O6-alkylguanine DNA alkyltransferase (OGAT) and a functional mismatch repair system. Temozolomide has antitumor and antiangiogenic effects.

3-甲基-4-氧代-3,4-二氢咪唑并[5,1-d][1,2,3,5]四嗪-8-甲酰胺；替莫唑胺

Temozolomide | NSC 362856 | CCRG 81045 | TMZ

化学品安全说明书(MSDS)

质检证书(COA)