首页 > 产品目录 > 信号通路 > Autophagy | 自噬 > (8S,11R,13S,14S,17R)-17-乙酰基-11-(4-(二甲基氨基)苯基)-13-甲基-3-氧代-2,3,6,7,8,11,12,13 ,14,15,16,17-十二氢-1H-环戊二烯并[a]菲-17-基乙酸酯；醋酸乌利司他；醋酸优力司特

(8S,11R,13S,14S,17R)-17-乙酰基-11-(4-(二甲基氨基)苯基)-13-甲基-3-氧代-2,3,6,7,8,11,12,13 ,14,15,16,17-十二氢-1H-环戊二烯并[a]菲-17-基乙酸酯；醋酸乌利司他；醋酸优力司特

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Ulipristal acetate (Synonyms: CDB-2914)

产品编号：CL2406A CAS No.：126784-99-4 MDLNo：MFCD00899035 分子式：C30H37NO4 分子量：475.62

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基本信息

英文名称	Ulipristal acetate (Synonyms: CDB-2914)
中文名称	(8S,11R,13S,14S,17R)-17-乙酰基-11-(4-(二甲基氨基)苯基)-13-甲基-3-氧代-2,3,6,7,8,11,12,13 ,14,15,16,17-十二氢-1H-环戊二烯并[a]菲-17-基乙酸酯；醋酸乌利司他；醋酸优力司特
CAS号	126784-99-4
分子式	C30H37NO4
分子量	475.62
MDL	MFCD00899035
外观	White to off-white powder
储存条件	Store short-term at 0-4°C or long-term at -20°C in a dry, dark place.

产品详情

lipristal acetate (CDB-2914) is an orally active selective progesterone receptor modulator (SPRM). It selectively stimulates autophagy in smooth muscle cells of fibroids. Ulipristal acetate has potential for the treatment of benign gynecological diseases, such as uterine fibroids.

相关文献

Autophagy up-regulation by ulipristal acetate as a novel target mechanism in the treatment of uterine leiomyoma: an in vitro study.

PMID: 31843092 DOI: 10.1016/j.fertnstert.2019.08.007

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Ulipristal acetate modulates the expression and functions of activin a in leiomyoma cells.

PMID: 25001022 DOI: 10.1177/1933719114542019

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Carcinogenicity and chronic rodent toxicity of the selective progesterone receptor modulator ulipristal acetate.

PMID: 23656453 DOI: 10.2174/15748863112079990012

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