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卡培他滨

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Capecitabine | RO 09-1978 | Xeloda

产品编号:CL2563 CAS No.:154361-50-9 MDLNo: 分子式:C15H22FN3O6 分子量:359.35
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基本信息
英文名称 Capecitabine | RO 09-1978 | Xeloda
中文名称卡培他滨
CAS号154361-50-9
分子式C15H22FN3O6
分子量359.35
外观White to off-white powder
储存条件Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years).
产品详情

Capecitabine is a fluoropyrimidine carbamate belonging to the class of antineoplastic agents called antimetabolites. As a prodrug, capecitabine is selectively activated by tumor cells to its cytotoxic moiety, 5-fluorouracil (5-FU); subsequently, 5-FU is metabolized to two active metabolites, 5-fluoro-2-deoxyuridine monophosphate (FdUMP) and 5-fluorouridine triphosphate (FUTP) by both tumor cells and normal cells. FdUMP inhibits DNA synthesis and cell division by reducing normal thymidine production, while FUTP inhibits RNA and protein synthesis by competing with uridine triphosphate for incorporation into the RNA strand.


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