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托西莫单抗

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Tositumomab

产品编号:CLA1115 CAS No.:208921-02-2 MDLNo: 分子式: 分子量:
规格 库存 目录价 会员专享价 数量
0.1 mg 3-5days ¥9000.00 登录后可见
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1 mg 3-5days ¥13000.00 登录后可见
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5 mg 3-5days ¥22000.00 登录后可见
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基本信息
英文名称 Tositumomab
中文名称托西莫单抗
CAS号208921-02-2
储存条件Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 2 to 8°C short term (1-2 weeks). Store at -20 °C 12 months. Store at -80°C long term.
产品详情

Tositumomab is a murine monoclonal antibody which targets the CD20 antigen produced in mammalian cell. It is classified as a IgG2a lambda antibody.This protein may be involved in the regulation of B-cell activation and proliferation. Defects in MS4A1 are the cause of immunodeficiency common variable type 5 (CVID5); also called antibody deficiency due to CD20 defect. CVID5 is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen. The defect results from a failure of B-cell differentiation and impaired secretion of immunoglobulins; the numbers of circulating B-cells is usually in the normal range, but can be low. Belongs to the MS4A family.

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