| 英文名称 | Deferasirox | ICL 670 | CGP-72670 |
|---|---|
| 中文名称 | 地拉罗司 |
| CAS号 | 201530-41-8 |
| 分子式 | C21H15N3O4 |
| 分子量 | 373.36 |
| 外观 | White to light brown powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
| 英文名称 | Deferasirox | ICL 670 | CGP-72670 |
|---|---|
| 中文名称 | 地拉罗司 |
| CAS号 | 201530-41-8 |
| 分子式 | C21H15N3O4 |
| 分子量 | 373.36 |
| 外观 | White to light brown powder |
| 储存条件 | Dry, dark and at 0 - 4 ℃ for short term (days to weeks) or -20 ℃ for long term (months to years). |
Deferasirox (CGP-72670) is an oral iron chelating agent used to treat chronic iron overload.
Inconsistent hepatic antifibrotic effects with the iron chelator deferasirox.
PMID: 25168203 DOI: 10.1111/jgh.12720
PMID: 23415674 DOI: 10.1016/j.exphem.2013.02.004
The oral iron chelator deferasirox induces apoptosis in myeloid leukemia cells by targetingcaspase.
PMID: 21951998 DOI: 10.1159/000330608